Dr. Opeyemi Ojueromi was recently celebrated as one of the 30 outstanding women scientists from Sub-Saharan Africa during the prestigious L’Oreal-UNESCO For Women in Science Awards held in Cotonou, Benin Republic.

This recognition highlights her innovative research on the integration of Citrus aurantium (marmalade orange) peel into yogurt as a potential treatment and preventive measure for malaria.

In this exclusive interview with Efosa Taiwo, Dr. Ojueromi shares her journey, inspirations, and the challenges she has faced as a scientist in Nigeria.

Congratulations on your award, Dr. Opeyemi! Could you share with us how your research into citrus-peel-enriched yoghurt began?

My interest in Citrus aurantium-peel-enriched yoghurt emerged from a blend of innate curiosity to understand the role of functional ingredients like marmalade orange (Citrus aurantium) peels play in ameliorating infectious including malaria. During my formative years, my parents would give us herbal drink made from Citrus aurantium peel whenever we fell ill, as a natural remedy for malaria. My findings revealed that these peels, often considered as waste, contain bioactive compounds such as polyphenols and alkaloids which have a profound effect in combating malaria, most especially by suppressing parasitic load, preventing inflammation and enhancing the antioxidant defense system which ultimately improves immune system.

What inspired you to explore its potential for malaria treatment?

My inspiration in exploring malaria treatment stemmed from an idea proposed by my mentor and postgraduate supervisor, Prof. Ganiyu Oboh, whose idea formed the foundation of my doctoral research: Being inspired by his guidance and that of my co-supervisor, Dr. Ayokunle Ademosun, I chose to continue this work during my postdoctoral studies to uncover more potential solutions to this deadly yet preventable disease. This ongoing research aims to contribute to new, effective treatments for malaria.

Why did you choose yoghurt as a medium for integrating citrus peels in your study?

I chose yogurt as a medium for integrating citrus peels in my study because it is a widely loved, delicious, and easily consumed drink, making it particularly suitable for children and pregnant women. Yogurt is not only a healthy drink, but it also contains beneficial live bacteria, such as Streptococcus thermophilus and Lactobacillus bulgaricus, which promote digestive health and support both the mother’s and baby’s well-being during pregnancy. The fortification of yogurt with citrus peel creates a synergistic effect, enhancing both its nutritional and medicinal properties, which could improve its potential as a natural remedy for malaria, especially in vulnerable populations.

Malaria continues to be a pressing issue in Nigeria. How do you envision your research contributing to the broader fight against malaria, particularly for children and pregnant women?

My research aims to provide an affordable, locally sourced treatment for vulnerable groups, especially children and pregnant women. By harnessing the natural properties of citrus peel and the probiotic benefits of yogurt, this approach could enhance immunity and support recovery from malaria in areas with limited access to conventional treatments. This sustainable solution could complement existing malaria interventions, contributing to the broader fight against the disease in Nigeria.

Beyond treatment, does your research also explore how this approach could be part of a preventive strategy for communities?

Yes, my research focuses on both preventive and treatment strategies.

What stage is your research currently at, and how soon do you think it could be scaled for public benefit?

The research is currently at the preliminary stage, with toxicological studies completed to ensure safety for consumption. Once we (my research team and I) have been able to finalize the main phase of the research, we will patent and commercialize our discoveries. We intend to form partnerships with reputable industries to bring the product to market, making it available to the public in the near future.

You’re balancing roles as a student, researcher, and possibly other responsibilities. How do you manage these different aspects of your life, and what drives you to keep going?

Balancing my roles as a postdoctoral researcher, wife, and mother is undoubtedly challenging, but with the support of my husband, family, mentors and friends, I’ve managed to navigate work-life balance effectively. The drive to push forward comes from my passion for scientific discovery and the desire to make a meaningful impact, especially as a woman scientist in Nigeria. This support network empowers me to thrive and continue to contribute to the advancement of research and the fight against pressing issues like malaria.

What challenges have you faced in conducting this research, especially in the context of Nigeria, and how have you overcome them?

Conducting malaria research in Nigeria has come with its own set of unique challenges, including limited resources and regulatory hurdles. These challenges are common in scientific research, especially in resource-constrained environments. However, I am making effort to surmount these obstacles through strategic collaborations and by securing creative funding solutions. These efforts, combined with perseverance and a strong commitment to my goal, have allowed me to move on with the research despite these difficulties.

Science, especially research, often comes with unique challenges. What message or advice would you give to young women in Nigeria who aspire to make breakthroughs in science and research?

To young women in Nigeria aspiring to excel in science and research, I would advise that they remain resilient, focused, and committed to their goals. By embracing challenges as opportunities for growth and seeking mentorship and support, they can unlock their full potential and achieve innovative and groundbreaking research.

What changes would you like to see in Nigeria to better support women in science and innovative research?

Nigeria should prioritize increased funding, mentorship, and inclusive policies to empower women in science and research. This will help female scientists reach their full potential, boosting innovation and national growth