By Sola Ogundipe
The Pfizer-BioNTech COVID-19 vaccine’s protection against “breakthrough” coronavirus infections wanes over time, according to new research.
The new study found that the vaccine’s ability to protect against infection was 88 percent in its first month, falling to 47 percent after just five months.
The study, funded by Pfizer and published n the journal Lancet, also provides strong new evidence that the waning immunity against infection probably would have been seen with or without the arrival of the Delta variant.
READ ALSO: Pfizer promotes healthcare advocacy with ‘Patients in Focus’
The Delta variant was not the driving factor in the vaccine’s waning efficacy against infection, according to the researchers’ findings, rather, the passage of time appeared to be the key to a vaccinated person’s resurgent vulnerability.
The research team led by infectious disease epidemiologist, Sara Tartof of Kaiser Permanente Southern California, found that a fresh inoculation with the Pfizer-BioNTech vaccine protected just as well against infection with the Delta variant as it did against infection with other versions of the coronavirus.
Also, the vaccine’s ability to protect vaccinated people from hospitalisation remained high across a span of time when the Delta variant gained ground in Southern California.
In addition, breakthrough infections were more closely linked to the amount of time that had lapsed since vaccination than they were to the particular viral variant involved.
By showing that waning immunity, not the Delta variant, was the likely reason for the rise in breakthrough infections, the study suggests it may not be necessary to reformulate a Pfizer-BioNTech booster that specifically targets Delta.
“For now, at least, a third shot identical to the first two would probably extend the vaccine’s early record of protection against all strains, including Delta,” Tartof said.
Disclaimer
Comments expressed here do not reflect the opinions of Vanguard newspapers or any employee thereof.