By Ayo Onikoyi

Mukhtar Idris, a biochemist at the Biochemistry and Biophysics Department at Oregon State University, Oregon, USA, has emphasised the significance of targeting cell surface proteins such as the Transmembrane Protease Serine 2 (TMPRSS2) protein in combating viral diseases, such as the coronavirus responsible for COVID-19.

He highlights the potential of African plants phytochemicals in inhibiting TMPRSS2, thus preventing viral entry into human cells.

“Understanding and targeting TMPRSS2 can help prevent the virus from invading the cell, offering a crucial window to curb an infection before it spreads,” states Idris.

Idris emphasized on the importance of traditional medicine in this pursuit, citing plants like Artemisia afra and Sutherlandia frutescens, traditionally used to treat respiratory infections, as potential sources of antiviral compounds.

According to him, he envisioned a future where treatments derived from these plants are not only effective but also accessible, especially in economically disadvantaged regions.

However, Idris acknowledges the challenges in transitioning from traditional use to clinical application.

He stressed the need for rigorous scientific validation to ensure the safety and efficacy of phytochemicals, as well as ethical considerations in bioprospecting to respect the rights of local communities.

Idris urges investment in this research area, emphasizing its potential to revolutionise antiviral therapy.

He advocated for the integration of diverse scientific traditions and knowledge systems, marrying cultural heritage with modern scientific rigor.

In conclusion, the integration of African plants phytochemicals into the global antiviral strategy represents an innovative approach to combating viral outbreaks.

 By valuing and investing in Africa’s rich biodiversity and traditional knowledge, we can develop new defenses against future pandemics, leveraging nature’s own solutions while fostering global cooperation in health innovation.